Pulmonary edema on a chip
نویسندگان
چکیده
منابع مشابه
Mathematical Modelling of Pulmonary Edema
The excess accumulation of water in lung interstitial or alveolar is called pulmonary edema which is caused by factors that upset the normal Starling balance in micro-circulation. Pulmonary edema disturbs the alveolar gas exchanges which are normally regulated by the respiratory system. Mathematical modelling of pulmonary edema may help to predict the lung conditions and the mechanisms involved...
متن کاملMathematical Modelling of Pulmonary Edema
The excess accumulation of water in lung interstitial or alveolar is called pulmonary edema which is caused by factors that upset the normal Starling balance in micro-circulation. Pulmonary edema disturbs the alveolar gas exchanges which are normally regulated by the respiratory system. Mathematical modelling of pulmonary edema may help to predict the lung conditions and the mechanisms involved...
متن کاملStudies on Pulmonary Edema
1. Bilateral cervical vagotomy in rabbits soon leads to death, usually within 8 to 24 hours. 2. Gradually increasing dyspnea, crises with expulsion of frothy, serous or sanguineous fluid from the mouth and nose, and terminal asphyxia are the important clinical features. 3. Postmortem examination reveals severe acute pulmonary edema and congestion, variable amounts of bronchopneumonia, and evide...
متن کاملPulmonary Edema
Pulmonary edema is a common problem in dogs and cats in both the emergency room and the intensive care unit. A good understanding of the physiology of fluid flow through the lungs is of paramount importance for developing techniques for rational patient management. The normal lung consists of a network of capillaries lined with endothelial cells, surrounding airspaces lined with alveolar epithe...
متن کاملA human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.
Preclinical drug development studies currently rely on costly and time-consuming animal testing because existing cell culture models fail to recapitulate complex, organ-level disease processes in humans. We provide the proof of principle for using a biomimetic microdevice that reconstitutes organ-level lung functions to create a human disease model-on-a-chip that mimics pulmonary edema. The mic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2012
ISSN: 1945-3477
DOI: 10.1038/scibx.2012.1251